Ah, interesting. You are configuring a queue and an RDP to “webhook” the messages out to a REST endpoint? Either way, no I don’t think it should be a problem. In fact, I think it should be less of a problem than having it configured the previous way.
Always best to test. I don’t know 100.000% off the top of my head. 
But hey, you could also implement my 1st suggestion where you just change the JMS connection factory to say “false” for text-msg-xml-payload and both should work the same… the Try Me! mini app should see it… and the outbound RDP REST API should convert it just the same.